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Once the treatment is underway, the treatment area becomes numb from the cold temperature of the device

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The analysts said a group of patients who eventually received the lowest maximum dose of the pill 90 milligrams still saw high rates of nausea "with limited weight loss efficacy." Another group of patients who took the highest maximum dose of the drug 120 milligrams with slightly lower dose increases over time had nausea rates of 83%, vomiting of 33% and diarrhea of 50%, according to the JPMorgan analysts

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